Wijzigingen

|traject=[[Essen Hbf]] - [[Bochum Hbf]] - [[Hagen Hbf]] - [[Letmathe]] - [[Iserlohn]]/[[Siegen]]

|materieel=[[FLIRT]]

}}

De '''RE16''' de [[Regional-Express]]-verbinding tussen [[Essen Hbf]], [[Hagen Hbf]], [[Letmathe]] en [[Iserlohn]]/[[Siegen]].